Description

(S)-2,5-Dihydro-3,6-Diethoxy-2-Isopropylpyrazine is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functionalized pyrazine core make it a valuable building block for creating complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), flavor and fragrance compounds, and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Flavor & Fragrance Industry: Used in the synthesis of complex, roasted, or nutty flavor compounds due to its pyrazine structure, which is common in many aroma molecules.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides where specific stereochemistry can influence biological efficacy.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic systems to induce stereoselectivity in chemical reactions.
• Academic & R&D: Used in chemical research for methodological studies in heterocyclic chemistry and stereoselective synthesis.
• Fine Chemical Synthesis: A versatile building block for creating other specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	(S)-2,5-Dihydro-3,6-Diethoxy-2-Isopropylpyrazine
CAS No.	134870-62-5
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	(S)-2-Isopropyl-3,6-diethoxy-2,5-dihydropyrazine; (S)-2,5-Dihydro-3,6-diethoxy-2-(1-methylethyl)pyrazine; (S)-3,6-Diethoxy-2-isopropyl-2,5-dihydropyrazine; (S)-2-Isopropyl-3,6-diethoxy-2H-pyrazine; (S)-DIEP; (S)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine; (S)-Flavor Pyrazine Intermediate; (S)-Enantiomer of Alkoxy Dihydropyrazine
EINECS	Contact for details

Quality Control

Our (S)-2,5-Dihydro-3,6-Diethoxy-2-Isopropylpyrazine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis (HPLC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided with every shipment to guarantee reproducible performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.