Description

Estradiol-3-Xyloside is a specific glycosylated derivative of the primary female sex hormone, estradiol. This compound is of significant interest in biochemical and pharmaceutical research due to its modified pharmacokinetic profile and receptor interaction compared to the parent hormone. It is primarily utilized by research institutions and pharmaceutical developers focusing on endocrinology, metabolic studies, and novel drug delivery systems. The precise structure of this xyloside conjugate makes it a valuable reference standard and a potential intermediate in the synthesis of more complex steroidal agents.

Application

• Biochemical Research: Used as a reference standard and probe in studies of estrogen metabolism, receptor binding affinity, and glycosylation effects on steroid hormone activity.
• Pharmaceutical Development: Serves as a key intermediate or precursor in the synthesis of novel steroidal compounds and targeted therapeutics.
• Endocrinology Studies: Employed in vitro and in vivo models to investigate the role of estrogen conjugates in physiological and pathological processes.
• Analytical Chemistry: Functions as a high-purity calibration standard for HPLC, LC-MS, and other chromatographic methods in analytical laboratories.
• Metabolite Identification: Critical for the identification and quantification of estrogen metabolites in complex biological matrices during ADME (Absorption, Distribution, Metabolism, and Excretion) studies.

Basic Information

Product Name	Estradiol-3-Xyloside
CAS No.	134366-08-8
Molecular Formula	C23H32O7
Molecular Weight	420.50 g/mol
Synonyms	Estradiol 3-β-D-xylopyranoside; 17β-Estradiol 3-(β-D-xylopyranoside); Estr-1,3,5(10)-triene-3,17β-diol 3-(β-D-xylopyranoside); 3-O-β-D-Xylopyranosyl-estradiol; Estradiol 3-xyloside; 17β-Estradiol-3-yl β-D-xylopyranoside
EINECS	Contact for details

Quality Control

Our Estradiol-3-Xyloside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.