Description

1-(Hexanoylthio)-2-Hexanoyl-3-Phosphatidylcholine is a synthetic, thioester-modified phospholipid derivative. This specialized compound is valued for its unique chemical structure, which combines a phosphatidylcholine backbone with hexanoylthio and hexanoyl functional groups, offering distinct reactivity and physicochemical properties. It is primarily utilized in advanced research and development within the pharmaceutical and life science sectors, particularly for probing lipid metabolism, membrane biophysics, and as a key intermediate in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research & Development: As a critical intermediate in the synthesis of novel drug candidates targeting lipid-related pathways and membrane-associated processes.
• Biochemical Research: Used as a substrate or probe in enzymatic studies, particularly for investigating phospholipase and acyltransferase activities.
• Lipidomics & Analytical Standards: Serves as a reference standard or internal standard in mass spectrometry-based lipid analysis for accurate quantification.
• Model Membrane Systems: Incorporated into liposomes or lipid bilayers to study the effects of thioester-modified lipids on membrane fluidity, stability, and protein-lipid interactions.
• Prodrug Synthesis: Potential use in the design of prodrugs where the thioester linkage allows for controlled release of active moieties.
• Specialty Chemical Intermediate: Employed in the custom synthesis of other complex, functionalized phospholipids for specific industrial or research applications.

Basic Information

Product Name	1-(Hexanoylthio)-2-Hexanoyl-3-Phosphatidylcholine
CAS No.	134153-58-5
Molecular Formula	C28H54NO8PS
Molecular Weight	595.76 g/mol
Synonyms	1-Hexanoylthio-2-hexanoyl-sn-glycero-3-phosphocholine; Hexanoylthio Phosphatidylcholine; 1-(Thiohexanoyl)-2-hexanoylphosphatidylcholine; PC(6:0/6:0-S); S-Hexanoyl Phosphatidylcholine; 1-S-Hexanoyl-2-hexanoyl-phosphatidylcholine; 1-(6-Thiohexanoyl)-2-hexanoyl-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-(Hexanoylthio)-2-Hexanoyl-3-Phosphatidylcholine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, NMR, and mass spectrometry. Specifications are designed to meet the exacting requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.