Description

2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-Ol is a high-purity, long-chain polyethylene glycol (PEG) derivative, specifically a monomethyl ether, known for its excellent solubility and biocompatibility. This compound is a critical functional intermediate for creating advanced materials with precise hydrophilic properties and controlled molecular architecture. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors who require reliable, high-quality PEGylation reagents and polymer precursors.

Application

• Pharmaceutical PEGylation: A key starting material for attaching polyethylene glycol chains to therapeutic proteins, peptides, and small molecule drugs to enhance solubility, prolong circulation time, and reduce immunogenicity.
• Bioconjugation & Linker Chemistry: Serves as a hydrophilic spacer or linker in the synthesis of antibody-drug conjugates (ADCs), diagnostic probes, and other bioconjugates.
• Polymer & Material Science: Used as a macroinitiator or monomer in the synthesis of block copolymers, hydrogels, and functionalized surfaces for biomedical and nanotechnology applications.
• Surface Modification: Employed to create non-fouling, protein-resistant coatings on medical devices, sensors, and nanoparticles to improve biocompatibility.
• Cosmetic & Personal Care Formulations: Acts as a solubilizer, moisturizer, and carrier in high-performance cosmetic products due to its non-toxic and skin-friendly properties.
• Lubricants & Functional Fluids: Utilized as a base or additive in specialty lubricants and heat transfer fluids where thermal stability and low toxicity are required.

Basic Information

Item	Details
Product Name	2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-Ol
CAS No.	133604-58-7
Molecular Formula	C41H84O17
Molecular Weight	849.1 g/mol
Synonyms	mPEG2000-OH; Poly(ethylene glycol) methyl ether (Mn ~2000); Methoxy polyethylene glycol 2000; PEG 2000 monomethyl ether; α-Methoxy-ω-hydroxy-poly(ethylene glycol); 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Polyoxyethylene (45) methyl ether
EINECS	Contact for details

Quality Control

Our 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, precise molecular weight distribution, and low levels of impurities such as diols and residual catalysts. Certificates of Analysis (COA) with detailed chromatographic data (GPC/HPLC) are provided to guarantee batch-to-batch consistency and compliance with your specific research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (nitrogen or argon), please contact our technical team.

Specification

Item	Specification
Appearance	White waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (NMR/HPLC)	≥ 95.0%
Average Molecular Weight (Mn)	1900 - 2100 Da
Polydispersity Index (PDI)	≤ 1.05
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.