Description

N,N,n-Trimethyl-D-Erythro-Sphingosine (Methyl Sulfate Salt) is a chemically modified sphingosine derivative, a key intermediate in the synthesis of complex sphingolipids and bioactive molecules. This high-purity compound is essential for researchers and manufacturers requiring precise control over sphingolipid metabolism and signaling pathways in biological systems. It is primarily utilized in advanced pharmaceutical research, particularly in oncology and immunology, for the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Research & Development: As a critical intermediate in the synthesis of sphingolipid-based drug candidates targeting cancer, inflammation, and metabolic disorders.
• Biochemical Research: Used as a tool compound to study sphingolipid metabolism, cell signaling pathways, apoptosis, and autophagy in vitro and in vivo.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and academic laboratories.
• Precursor for Labeled Compounds: Acts as a starting material for the synthesis of isotopically labeled (e.g., deuterated, 13C) sphingolipids for mass spectrometry and tracer studies.
• Lipidomics: Employed in the preparation of calibration standards and internal standards for quantitative lipidomic analysis.

Basic Information

Product Name	N,N,n-Trimethyl-D-Erythro-Sphingosine (Methyl Sulfate Salt)
CAS No.	133561-52-1
Molecular Formula	C23H49NO5S
Molecular Weight	451.71 g/mol
Synonyms	D-erythro-Sphingosine, N,N,N-trimethyl-, methyl sulfate (salt); N,N,N-Trimethylsphingosine Methyl Sulfate; TMS Methyl Sulfate; N,N,N-Trimethyl-D-erythro-sphingosine, methosulfate; FTY720 Methyl Sulfate precursor; Sphingosine, N,N,N-trimethyl-, methyl sulfate, D-erythro-; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol, N,N,N-trimethyl-, methyl sulfate (salt)
EINECS	Contact for details

Quality Control

Our N,N,n-Trimethyl-D-Erythro-Sphingosine (Methyl Sulfate Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.