Description

2-Piperazinemethanol, 4-Acetyl-, (S)- (9Ci) CAS NO 133407-36-0 is a chiral piperazine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically enriched compounds.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental profile.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value specialty chemicals requiring precise molecular architecture.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Piperazinemethanol, 4-Acetyl-, (S)- (9Ci)
CAS No.	133407-36-0
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(S)-1-Acetyl-4-(hydroxymethyl)piperazine; (S)-4-Acetyl-2-piperazinemethanol; (S)-N-Acetylpiperazine methanol; 1-Acetyl-4-(hydroxymethyl)piperazine, (S)-; 4-Acetyl-2-piperazinemethanol, (S)-; (S)-1-(Hydroxymethyl)-4-acetylpiperazine; (S)-4-(Hydroxymethyl)-1-acetylpiperazine
EINECS	Contact for details

Quality Control

Our 2-Piperazinemethanol, 4-Acetyl-, (S)- is produced under strict quality management systems. We offer material suitable for research and development use, with typical purity levels exceeding 95% (by HPLC). Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and residual solvent content are provided with each batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.