Description

cis-4-Amino-1-Benzylpiperidin-3-Ol is a versatile piperidine derivative and a key chiral building block in organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it for constructing complex molecules, particularly in the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates.
• API Synthesis: Used in constructing the core scaffold of potential Active Pharmaceutical Ingredients, particularly in neurological and psychiatric applications.
• Fine Chemical Production: Serves as a building block for complex, high-value specialty chemicals and ligands.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Catalyst & Ligand Preparation: Useful in the synthesis of chiral catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	cis-4-Amino-1-Benzylpiperidin-3-Ol
CAS No.	133341-84-1
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	4-Amino-1-benzyl-3-piperidinol; 1-Benzyl-4-amino-3-piperidinol; 3-Piperidinol, 4-amino-1-(phenylmethyl)-, cis-; 4-Amino-1-benzylpiperidin-3-ol; cis-1-Benzyl-4-aminopiperidin-3-ol; (3R,4S)-4-Amino-1-benzylpiperidin-3-ol (for specific stereoisomer); 1-Benzyl-cis-4-amino-3-piperidinol
EINECS	Contact for details

Quality Control

Our cis-4-Amino-1-Benzylpiperidin-3-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.