Description

Fedotozine D(-)-Tartrate is a high-purity, enantiomerically pure salt form of the selective σ-1 receptor agonist, fedotozine. This compound is critical for pharmaceutical research and development, particularly in the study of visceral pain modulation and gastrointestinal disorders. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in preclinical studies and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
• Preclinical Research: Used in in vitro and in vivo studies to investigate the pharmacology of σ-1 receptors.
• Drug Discovery & Development: A key intermediate or active pharmaceutical ingredient (API) in the development of new analgesics targeting visceral pain.
• Biochemical Assays: Employed in high-throughput screening and receptor binding assays to identify and characterize new drug candidates.
• Metabolic and Pharmacokinetic Studies: Utilized to study the absorption, distribution, metabolism, and excretion (ADME) profiles of fedotozine.

Basic Information

Product Name	Fedotozine D(-)-Tartrate
CAS No.	133267-27-3
Molecular Formula	C24H33N3O8
Molecular Weight	491.54 g/mol
Synonyms	Fedotozine (D-(-)-Tartrate); Fedotozine D-(-)-Tartrate Salt; (R)-Fedotozine Tartrate; JO-1196 (D-(-)-Tartrate); 4-[(2R)-2-[[(2R,3R)-2-(3,4-Dichlorophenyl)-4-oxo-1,3-thiazolidin-3-yl]methyl]-1-piperazinyl]-2,2-diphenylbutanenitrile (2R,3R)-2,3-Dihydroxysuccinate; Fedotozine L-Tartrate (enantiomer)
EINECS	Contact for details

Quality Control

Our Fedotozine D(-)-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) providing results for identity, purity, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.