Description

5-Aminosalicylic Acid Sodium Salt is the sodium salt derivative of mesalamine, a key pharmaceutical intermediate with significant therapeutic relevance. This compound is valued for its enhanced stability and solubility profile compared to its parent acid, making it a critical component in advanced drug formulations. It is primarily required by manufacturers in the pharmaceutical industry for the production of anti-inflammatory medications targeting gastrointestinal conditions.

Application

• Pharmaceutical Active Ingredient (API): Serves as a primary intermediate in the synthesis of mesalamine (5-aminosalicylic acid) for the treatment of ulcerative colitis and Crohn's disease.
• Controlled-Release Formulations: Used in the development of enteric-coated tablets and sustained-release drug delivery systems to ensure targeted release in the colon.
• Research & Development: Employed in preclinical and clinical research for investigating new inflammatory bowel disease (IBD) therapies and drug delivery mechanisms.
• Analytical Reference Standard: Functions as a high-purity standard in quality control laboratories for HPLC, UV, and other analytical methods to assay commercial drug products.
• Chemical Synthesis: Acts as a versatile building block for the synthesis of more complex azo compounds and other salicylate derivatives.

Basic Information

Product Name	5-Aminosalicylic Acid Sodium Salt
CAS No.	35589-28-7
Molecular Formula	C7H6NNaO3
Molecular Weight	175.12 g/mol
Synonyms	Mesalamine Sodium Salt; Sodium 5-aminosalicylate; Sodium Mesalazine; 5-ASA Sodium Salt; 5-Amino-2-hydroxybenzoic Acid Sodium Salt; Mesalazine Sodium; Sodium 5-Amino-2-hydroxybenzoate
EINECS	Contact for details

Quality Control

Our 5-Aminosalicylic Acid Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
pH (5% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.