Description

1,4-Piperazinedicarboxylic Acid, 2-(1-Methylethyl)-, 1,4-Di(Phenylmethyl) Ester, (2S)- is a high-purity, chiral piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, where its specific stereochemistry and functional groups enable precise chemical modifications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Ligand and Catalyst Development: Serves as a core structure for designing novel ligands and organocatalysts used in fine chemical manufacturing.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics, which are molecules that mimic the biological activity of peptides.
• Chemical Biology Probes: Used to create specialized probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis Projects: A critical starting material for contract research organizations (CROs) and CDMOs working on client-specific, complex organic molecules.

Basic Information

Product Name	1,4-Piperazinedicarboxylic Acid, 2-(1-Methylethyl)-, 1,4-Di(Phenylmethyl) Ester, (2S)-
CAS No.	133181-65-4
Molecular Formula	C24H30N2O4
Molecular Weight	410.51 g/mol
Synonyms	(2S)-2-Isopropyl-1,4-bis(phenylmethyl) piperazine-1,4-dicarboxylate; (S)-2-Isopropyl-1,4-dibenzyl piperazine-1,4-dicarboxylate; 1,4-Dibenzyl (2S)-2-isopropylpiperazine-1,4-dicarboxylate; (S)-1,4-Dibenzyl 2-isopropylpiperazine-1,4-dicarboxylate; 1,4-Piperazinedicarboxylic acid, 2-(1-methylethyl)-, 1,4-bis(phenylmethyl) ester, (2S)-; L-2-Isopropyl-1,4-dibenzyl piperazine-1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing lot-specific results are available upon request. Our quality management system supports the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.