Description

3-(Piperazin-1-Yl)Benzo[D]Isothiazole Dihydrochloride is a high-purity, functionalized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, combining a benzoisothiazole core with a piperazine moiety, making it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly in the areas of central nervous system (CNS) and anti-infective drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Chemical Research & Development: Used as a versatile scaffold for constructing complex molecular libraries in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural unit in the manufacturing process of specific APIs.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor-ligand interactions due to its heterocyclic structure.
• Agrochemical Development: Potential intermediate for creating new crop protection agents and pesticides.
• Material Science: Investigated for its potential use in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	3-(Piperazin-1-Yl)Benzo[D]Isothiazole Dihydrochloride
CAS No.	133070-64-1
Molecular Formula	C11H14N3S · 2HCl
Molecular Weight	309.23 g/mol
Synonyms	3-(1-Piperazinyl)-1,2-benzisothiazole Dihydrochloride; 3-Piperazin-1-yl-1,2-benzothiazole Dihydrochloride; Benzo[d]isothiazol-3-yl-piperazine Dihydrochloride; 1,2-Benzisothiazol-3-ylpiperazine Dihydrochloride; 3-(Piperazin-1-yl)benzo[d]isothiazole Dihydrochloride; 3-Piperazinylbenzoisothiazole Dihydrochloride; 133070-64-1 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(Piperazin-1-Yl)Benzo[D]Isothiazole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.