Description

2,4,6-Trimethylbenzylmagnesium Chloride is a highly reactive organometallic Grignard reagent, essential for introducing the sterically hindered 2,4,6-trimethylbenzyl (mesitylmethyl) group into target molecules. This compound matters for its role in constructing complex organic frameworks, particularly in the synthesis of fine chemicals and advanced materials where precise molecular architecture is critical. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing sterically hindered carbon skeletons found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators requiring specific molecular shapes.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials with tailored properties.
• Fine Chemical Manufacturing: Facilitates carbon-carbon bond formation in the multi-step synthesis of complex fragrance, flavor, and dye molecules.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical spaces in organic synthesis laboratories.

Basic Information

Item	Details
Product Name	2,4,6-Trimethylbenzylmagnesium Chloride
CAS No.	132856-34-9
Molecular Formula	C10H13ClMg
Molecular Weight	192.96 g/mol
Synonyms	(2,4,6-Trimethylphenyl)methylmagnesium Chloride; Mesitylmethylmagnesium Chloride; (Mesitylmethyl)magnesium Chloride; 2,4,6-Trimethylbenzylmagnesium Chloride solution; Trimethylbenzylmagnesium Chloride; Grignard reagent, (2,4,6-trimethylbenzyl)magnesium chloride; (2,4,6-Trimethylbenzyl)magnesium chloride
EINECS	Contact for details

Quality Control

Our 2,4-6-Trimethylbenzylmagnesium Chloride is produced and handled under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent composition, to ensure consistency and reliability for your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, store at recommended temperatures as specified on the label, typically between 2°C and 8°C for extended stability. Keep away from moisture, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration (in specified solvent)	0.5 M - 2.0 M (Typical in THF or Diethyl Ether)
Assay (Titration)	≥ 95%
Identity (IR / NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.