Description

Piperazine, 1-Cyclobutyl- is a specialized heterocyclic organic compound belonging to the piperazine class, featuring a cyclobutyl substituent. This structural motif makes it a valuable versatile building block in advanced organic synthesis, particularly for creating complex molecules with specific pharmacological or material properties. It is primarily sought after by pharmaceutical research and development teams and fine chemical manufacturers for the development of new active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, potentially for central nervous system (CNS) agents, antivirals, or other therapeutic classes.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, or fungicides where the piperazine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis or metal complexation.
• Material Science Research: Employed in the synthesis of polymers, dyes, or other advanced materials requiring a rigid, functionalized amine component.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Piperazine, 1-Cyclobutyl-
CAS No.	132800-13-6
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	1-Cyclobutylpiperazine; N-Cyclobutylpiperazine; Cyclobutylpiperazine; 1-(Cyclobutyl)piperazine; Piperazine, N-cyclobutyl-; 1-Piperazinecyclobutane
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, and NMR, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.