Description

4-(2-Hydroxy-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-purity chemical intermediate, primarily valued for its role as a key building block in sophisticated organic synthesis. Its core value proposition lies in providing a protected piperazine scaffold with a reactive hydroxyl handle, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• API Synthesis: Used in constructing complex molecular architectures for active pharmaceutical ingredients, leveraging its protected amine and functional hydroxyl group.
• Peptidomimetics & Bioconjugation: Serves as a linker or spacer molecule in the design of peptide mimics and for bioconjugation applications in drug delivery systems.
• Ligand & Catalyst Development: Employed in the research and development of specialized ligands for metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) requiring high-purity, bespoke intermediates.
• Agrochemical Research: Potential intermediate in the development of advanced herbicides, fungicides, or plant growth regulators.

Basic Information

Item	Details
Product Name	4-(2-Hydroxy-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	132710-90-8
Molecular Formula	C13H26N2O3
Molecular Weight	258.36 g/mol
Synonyms	1-Boc-4-(2-hydroxypropyl)piperazine; tert-Butyl 4-(2-hydroxypropyl)piperazine-1-carboxylate; 4-(2-Hydroxypropyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(2-hydroxypropyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-hydroxypropyl)piperazine; Piperazine, 4-(2-hydroxypropyl)-, 1-(1,1-dimethylethyl) ester; BOC-Piperazine-OH-Propyl
EINECS	Contact for details

Quality Control

Our 4-(2-Hydroxy-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.