Description

6-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules with potential biological activity, offering a unique piperazine-pyridine scaffold. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Synthesis Reagent: Serves as a versatile precursor for creating complex piperazine and pyridine derivatives in academic and industrial laboratories.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and specialty materials.

Basic Information

Product Name	6-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Ethyl Ester
CAS No.	132521-78-9
Molecular Formula	C12H17N3O2
Molecular Weight	235.28 g/mol
Synonyms	Ethyl 6-(piperazin-1-yl)nicotinate; 6-Piperazin-1-yl-nicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 6-(1-piperazinyl)-, ethyl ester; Ethyl 6-(1-piperazinyl)-3-pyridinecarboxylate; 132521-78-9; 6-(Piperazin-1-yl)nicotinic acid ethyl ester; Ethyl 6-piperazin-1-ylpyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.