Description

tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrrole class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities (NCEs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients (APIs) that incorporate the fused pyrrolopyrrole core structure.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Process Development: Employed in the development and scale-up of robust and efficient synthetic routes for pilot and commercial-scale production.
• Academic Research: Used in university and institutional laboratories for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate
CAS No.	132414-81-4
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 1,3,3a,4,6,6a-Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate; 1-Boc-3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-b]pyrrole; 1H-Pyrrolo[3,4-b]pyrrole-5(1H)-carboxylic acid, 1,3,3a,4,6,6a-hexahydro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl Hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate; Boc-HHP; tert-Butyl Hexahydro-1H-pyrrolo[3,4-b]pyrrole-5(1H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.