Description

2,3-Piperazinedione, 1-Acetyl- (9Ci) is a heterocyclic organic compound belonging to the piperazinedione class, serving as a versatile chemical intermediate. Its value lies in its functionalized diketopiperazine core, which is a privileged scaffold in medicinal chemistry for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Peptidomimetic Development: Serves as a constrained dipeptide mimic (diketopiperazine) in the design of bioactive peptides with enhanced metabolic stability.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing fused heterocyclic systems and other complex organic molecules.
• Agrochemical Research: Potential intermediate in the development of novel pesticides and herbicides due to its bioactive heterocyclic structure.

Basic Information

Product Name	2,3-Piperazinedione, 1-Acetyl- (9Ci)
CAS No.	132269-98-8
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	1-Acetyl-2,3-piperazinedione; 1-Acetylpiperazine-2,3-dione; N-Acetyldiketopiperazine; Acetyl Diketopiperazine; 1-Acetyl-2,3-diketopiperazine; 1-Acetyl-2,3-dioxopiperazine; 2,3-Dioxo-1-acetylpiperazine; 1-Acetyl-2,3-piperazinedione (9CI)
EINECS	Contact for details

Quality Control

Our 2,3-Piperazinedione, 1-Acetyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents, supporting its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.