Description

1-(T-Butoxycarbonyl)-4-(2-Nitroimidazol-1-Ylacetyl)Piperazine is a specialized heterocyclic building block of significant interest in advanced pharmaceutical synthesis. This compound is valued for its role as a key intermediate in the development of novel therapeutic agents, particularly those targeting hypoxic conditions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of bioreductive prodrugs and diagnostic imaging agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of hypoxia-targeting nitroimidazole-based drugs and prodrugs.
• Bioreductive Prodrug Development: Used in research for creating compounds activated under low-oxygen conditions, relevant in oncology.
• Diagnostic Agent Synthesis: Serves as a building block for potential PET (Positron Emission Tomography) radiotracers used to image tumor hypoxia.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new chemical entities with enhanced therapeutic profiles.
• API (Active Pharmaceutical Ingredient) Manufacturing: Used in the controlled, multi-step synthesis of complex active ingredients.
• Chemical Biology Probes: Can be utilized to develop tools for studying biological processes related to cellular oxygen levels.

Basic Information

Product Name	1-(T-Butoxycarbonyl)-4-(2-Nitroimidazol-1-Ylacetyl)Piperazine
CAS No.	131339-74-7
Molecular Formula	C14H21N5O5
Molecular Weight	339.35 g/mol
Synonyms	1-Boc-4-(2-nitro-1H-imidazol-1-ylacetyl)piperazine; 1-(tert-Butoxycarbonyl)-4-[(2-nitro-1H-imidazol-1-yl)acetyl]piperazine; 4-[(2-Nitro-1H-imidazol-1-yl)acetyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-4-(2-nitroimidazol-1-ylacetyl)piperazine; tert-Butyl 4-(2-nitro-1H-imidazol-1-ylacetyl)piperazine-1-carboxylate; BOC-Nitroimidazole-Piperazine; 131339-74-7
EINECS	Contact for details

Quality Control

Our 1-(T-Butoxycarbonyl)-4-(2-Nitroimidazol-1-Ylacetyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.