Description

(+/-)14(15)-Epoxy-5Z,8Z,11Z,17Z-Eicosatetraenoic Acid CAS NO 131339-24-7 is a specialized eicosanoid derivative, specifically an epoxyeicosatetraenoic acid (EET) regioisomer, that serves as a critical biochemical intermediate. This compound is valued for its role in lipid signaling pathways, particularly in the study of cytochrome P450-mediated arachidonic acid metabolism. It is primarily sought by researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors for use as a reference standard, a synthetic precursor, and a tool for investigating cardiovascular, renal, and inflammatory processes.

Application

• Biomedical Research: Used as a high-purity reference standard and analytical standard in lipidomics and metabolomics studies.
• Pharmacological Studies: Serves as a key biochemical tool for investigating the biological activity and signaling mechanisms of epoxyeicosatrienoic acids (EETs) and their analogs.
• Drug Discovery & Development: Acts as a synthetic intermediate or a lead compound scaffold for developing novel therapeutics targeting hypertension, inflammation, and pain.
• Enzyme Activity Assays: Employed in vitro to study the activity and inhibition of soluble epoxide hydrolase (sEH) and cytochrome P450 epoxygenases.
• Cell Signaling Research: Utilized to probe the role of epoxy fatty acids in cellular processes such as vasodilation, angiogenesis, and anti-inflammatory responses.
• Academic Research: Fundamental research tool in university and institutional labs focusing on lipid biochemistry and eicosanoid pharmacology.

Basic Information

Product Name	(+/-)14(15)-Epoxy-5Z,8Z,11Z,17Z-Eicosatetraenoic Acid
CAS No.	131339-24-7
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	14,15-EpETE; 14(15)-Epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic Acid; (±)14,15-Epoxyeicosatetraenoic Acid; 14,15-Epoxyeicosatetraenoic Acid; EET analog; 14,15-Epoxy-5,8,11,17-eicosatetraenoic Acid; 14(15)-EpETE; Arachidonic acid 14,15-epoxide
EINECS	Contact for details

Quality Control

Our (+/-)14(15)-Epoxy-5Z,8Z,11Z,17Z-Eicosatetraenoic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material for GLP or GMP-regulated work upon request and qualification.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)
Solubility	Soluble in DMSO, ethanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.