Description

17,18-Epoxy-5,8,11,14-Eicosatetraenoic Acid is a specialized epoxy fatty acid derivative of eicosatetraenoic acid, representing a key intermediate and bioactive molecule in lipid research. This compound is of significant interest for its role in studying cytochrome P450 (CYP) epoxygenase pathways and the metabolism of polyunsaturated fatty acids (PUFAs). It is primarily utilized by researchers and developers in the pharmaceutical, nutraceutical, and advanced biochemical synthesis sectors.

Application

• Biochemical Research Standard: Used as a reference standard in lipidomics and metabolomics studies to investigate eicosanoid and epoxy fatty acid pathways.
• Pharmaceutical R&D: Serves as a critical intermediate in the development of novel therapeutic agents targeting inflammation, cardiovascular diseases, and metabolic disorders.
• Enzyme Activity Studies: Employed as a substrate to study the activity and inhibition of soluble epoxide hydrolase (sEH) and cytochrome P450 enzymes.
• Cell Signaling Research: Investigated for its potential role as a lipid mediator in cellular signaling and physiological regulation.
• Analytical Method Development: Used to develop and validate analytical methods such as LC-MS/MS for the detection and quantification of epoxy fatty acids in biological matrices.
• Nutraceutical Research: Explored for its bioactive properties in the context of dietary supplements and functional food ingredient development.

Basic Information

Item	Details
Product Name	17,18-Epoxy-5,8,11,14-Eicosatetraenoic Acid
CAS No.	131339-23-6
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	17,18-EpETE; 17(18)-Epoxy-5,8,11,14-eicosatetraenoic Acid; 17,18-Epoxyeicosatetraenoic Acid; 17,18-EEQ; (17R,18S)-Epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 17,18-Epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 17(18)-EpETE; 17,18-Epoxy Eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 17,18-Epoxy-5,8,11,14-Eicosatetraenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)
Solubility	Soluble in ethanol, DMSO, DMF; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.