Description

Ethanone, 1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci) CAS NO 131328-27-3 is a chiral, non-racemic ketone derivative featuring a tetrahydrofuran moiety, serving as a valuable synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and functional group make it a critical building block for the synthesis of complex, biologically active molecules. This high-purity compound is essential for research and development in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing complex heterocyclic structures.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Fragrance & Flavor Chemistry: Serves as a starting material for the synthesis of sophisticated aroma chemicals and flavor compounds due to its furan-derived backbone.
• Agrochemical Research: Employed in the development of novel, chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials.
• Academic & R&D Laboratories: A crucial reagent for methodological development in organic synthesis and medicinal chemistry research at universities and corporate R&D centers.

Basic Information

Product Name	Ethanone, 1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci)
CAS No.	131328-27-3
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(S)-1-(Tetrahydrofuran-2-yl)ethanone; (2S)-1-(Oxolan-2-yl)ethanone; 1-[(2S)-Tetrahydro-2-furanyl]ethanone; (S)-2-Acetyltetrahydrofuran; L-2-Acetyltetrahydrofuran; (S)-(-)-2-Acetyltetrahydrofuran; 131328-27-3; (S)-1-(Tetrahydro-2-furanyl)ethanone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC, GC, NMR, and optical rotation measurement. A detailed Certificate of Analysis (COA) documenting identity, purity, assay, and enantiomeric excess is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.