Description

2-Piperazineacetamide,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci) is a high-purity, stereochemically defined piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecules with precise three-dimensional architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of protease inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for targeted therapies.
• Protease Inhibitor Synthesis: Serves as a core structural motif in the design and synthesis of potential enzyme inhibitors.
• Agrochemical Research: Used in creating novel, stereospecific active ingredients for crop protection products.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a scaffold for combinatorial chemistry libraries.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in asymmetric synthesis and heterocyclic chemistry.
• Peptidomimetic Development: Used in the design of peptide analogs with improved metabolic stability and bioavailability.

Basic Information

Product Name	2-Piperazineacetamide,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci)
CAS No.	131025-37-1
Molecular Formula	C7H11N3O3
Molecular Weight	185.18 g/mol
Synonyms	(2S,5S)-5-Methyl-3,6-dioxo-2-piperazineacetamide; (2S,5S)-5-Methyl-3,6-dioxopiperazin-2-ylacetamide; L-5-Methyl-3,6-dioxopiperazine-2-acetamide; (2S,5S)-5-Methyl-3,6-dioxopiperazine-2-acetamide; 2-Piperazineacetic acid, 5-methyl-3,6-dioxo-, amide, (2S,5S)-; (2S,5S)-5-Methyl-3,6-dioxo-2-piperazineacetic acid amide
EINECS	Contact for details

Quality Control

Our 2-Piperazineacetamide,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.