Description

1-o-Oleoyl-3-Chloro-3-Deoxy-2-Phosphatidylcholine is a synthetic, chemically modified phospholipid derivative of significant interest in advanced biochemical and pharmaceutical research. This compound serves as a crucial intermediate and functional analog for studying membrane biophysics, lipid metabolism, and targeted drug delivery systems. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers focused on liposome formulation, prodrug development, and cell signaling pathway investigation.

Application

• Lipidomics and Membrane Research: As a structurally defined, modified phospholipid for studying membrane fluidity, protein-lipid interactions, and model membrane systems.
• Drug Delivery Systems: A key component in the design and synthesis of novel liposomal and nanoparticle-based carriers for targeted therapeutic delivery.
• Biochemical Probe Development: Used to create labeled or tagged phospholipid analogs for tracking metabolic pathways and enzymatic activity.
• Pharmaceutical Intermediate: Serves as a critical synthetic building block in the production of specialized active pharmaceutical ingredients (APIs) and prodrugs.
• Cell Biology Studies: Employed in research to investigate the role of specific phospholipid modifications in cell signaling, apoptosis, and other cellular processes.

Basic Information

Item	Details
Product Name	1-o-Oleoyl-3-Chloro-3-Deoxy-2-Phosphatidylcholine
CAS No.	131024-85-6
Molecular Formula	C44H85ClNO7P
Molecular Weight	806.57 g/mol
Synonyms	3-Chloro-3-deoxy-2-oleoyl-sn-glycero-1-phosphocholine; 1-Oleoyl-2-hydroxy-3-chloro-3-deoxy-sn-glycerophosphocholine; 3-Chloro-3-deoxy-1-oleoyl-2-lyso-phosphatidylcholine; Chlorodeoxyphosphatidylcholine (oleoyl); Modified Lyso-PC; 3-Cl-3-deoxy-LPC(18:1); Phospholipid analog 131024-85-6
EINECS	Contact for details

Quality Control

Our 1-o-Oleoyl-3-Chloro-3-Deoxy-2-Phosphatidylcholine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.