Description

1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro-1-Methyl- (9Ci) is a high-value, reactive chemical intermediate essential for constructing complex molecular architectures. Its core value lies in its ability to act as a versatile acylating agent, facilitating the efficient synthesis of amides and esters under controlled conditions. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the benzimidazole scaffold's prevalence in bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and insecticides, where the tetrahydrobenzimidazole core contributes to biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers, ligands for catalysis, and organic electronic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling proteins, peptides, or other biomolecules via its reactive carbonyl chloride group.

Basic Information

Product Name	1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro-1-Methyl- (9Ci)
CAS No.	131020-45-6
Molecular Formula	C9H11ClN2O
Molecular Weight	198.65 g/mol
Synonyms	4,5,6,7-Tetrahydro-1-methyl-1H-benzimidazole-5-carbonyl chloride; 1-Methyl-4,5,6,7-tetrahydro-1H-benzimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-benzimidazole; 1-Methyl-4,5,6,7-tetrahydrobenzimidazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro-1-Methyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP-compliant applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.