Description

Bruceine I is a bioactive quassinoid compound isolated from the seeds of Brucea javanica, known for its significant pharmacological potential. This high-purity reference standard is essential for research and development in drug discovery and natural product chemistry. It is primarily sought by pharmaceutical researchers, analytical laboratories, and manufacturers of herbal extracts and dietary supplements for use in bioactivity studies and quality control protocols.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of Brucea javanica extracts and related products.
• Drug Discovery & Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in preclinical studies investigating anti-cancer, anti-parasitic, and anti-inflammatory activities.
• Natural Product Analysis: Employed in analytical methods development and validation for HPLC, LC-MS, and TLC to quantify bruceine content in complex botanical matrices.
• Herbal Medicine Quality Control: Critical for standardizing herbal preparations and ensuring batch-to-batch consistency in finished products containing Brucea javanica.
• Academic & Institutional Research: Used in university and government laboratories for pharmacological, toxicological, and metabolic pathway studies.

Basic Information

Product Name	Bruceine I
CAS No.	130705-31-6
Molecular Formula	C20H28O9
Molecular Weight	412.43 g/mol
Synonyms	Bruceine A; (1S,2R,6S,7S,8S,11S,12R,13S,15R,17S)-11,12,13,15-Tetrahydroxy-6,7,8-trimethyl-16-methylidene-14-oxapentacyclo[9.5.2.01,8.02,6.012,17]octadecane-4,9,18-trione; NSC 165563; Yadanziolide C
EINECS	Contact for details

Quality Control

Our Bruceine I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.