Description

4-(4-Nitrophenethyl)Piperazine-1-Carboxylic Acid Tert Butyl Ester is a specialized piperazine derivative and a key protected intermediate in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of complex pharmaceutical molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable piperazine and protected amine functionalities.
• Peptidomimetic Synthesis: Serves as a scaffold for creating peptidomimetics and other biologically active molecules that mimic peptide structures.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Chemical Biology Probes: Used in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	4-(4-Nitrophenethyl)Piperazine-1-Carboxylic Acid Tert Butyl Ester
CAS No.	130636-60-1
Molecular Formula	C18H27N3O4
Molecular Weight	349.43 g/mol
Synonyms	1-Boc-4-(4-Nitrophenethyl)piperazine; tert-Butyl 4-(4-nitrophenethyl)piperazine-1-carboxylate; 4-(4-Nitrophenethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-[2-(4-nitrophenyl)ethyl]-1-piperazinecarboxylate; 4-(2-(4-Nitrophenyl)ethyl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-(4-nitrophenethyl)piperazine; N-Boc-4-(4-nitrophenethyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrophenethyl)Piperazine-1-Carboxylic Acid Tert Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.