Description

1-Palmitoyl-2-Isolinoleoyl Phosphatidylcholine is a high-purity, semi-synthetic phospholipid with a defined fatty acid composition. This compound is a critical component for creating advanced lipid-based delivery systems and biomimetic membranes due to its specific structural properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetics industries for applications requiring precise lipid formulation.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for creating stable, uniform liposomes and lipid nanoparticles (LNPs) for drug and gene delivery.
• Biomembrane Research: Used as a standard or model membrane component in biophysical studies to investigate membrane fluidity, permeability, and protein-lipid interactions.
• Pharmaceutical Excipient: Serves as an emulsifying and solubilizing agent in injectable and topical formulations to enhance bioavailability.
• Nutraceutical Encapsulation: Employed in the encapsulation of sensitive bioactive compounds (e.g., vitamins, ω-3s) to improve stability and targeted release.
• Advanced Cosmetics: Incorporated into high-performance skincare products like nanosomes for improved active ingredient penetration and skin barrier repair.
• Cell Culture & Diagnostics: Used in serum-free media supplements and as a coating agent for cell culture surfaces or diagnostic assays.

Basic Information

Product Name	1-Palmitoyl-2-Isolinoleoyl Phosphatidylcholine
CAS No.	130614-06-1
Molecular Formula	C46H86NO8P
Molecular Weight	812.15 g/mol
Synonyms	PC(16:0/18:2(9Z,12Z)); Phosphatidylcholine (16:0/18:2); 1-Hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; POPC (common trade name variant, though not strictly accurate); Isolinoleoyl Palmitoyl Phosphatidylcholine; Defined Phospholipid; sn-Glycero-3-phosphocholine derivative; L-α-Phosphatidylcholine, palmitoyl-isolinoleoyl
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Isolinoleoyl Phosphatidylcholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets the stringent requirements for research and GMP-grade applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term stability, the product should be kept desiccated. Allow the sealed vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or lyophilized powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Palmitic acid (C16:0): 45-55%; Linoleic acid (C18:2): 45-55%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.