Description

Bimoclomol is a synthetic, small-molecule co-inducer of heat shock proteins (HSPs) with significant pharmacological research interest. Its core value lies in its ability to modulate cellular stress response pathways, offering a potential therapeutic mechanism for conditions involving protein misfolding and aggregation. This makes it a critical compound for pharmaceutical R&D and preclinical studies in areas such as neuroprotection and cytoprotection. Bimoclomol CAS NO 130493-03-7 is primarily utilized by research institutions and pharmaceutical developers focused on novel treatment strategies.

Application

• Pharmaceutical Research & Development: As a lead compound or reference standard in the discovery of cytoprotective and neuroprotective agents.
• Preclinical Studies: Investigation of therapeutic efficacy in animal models for neurodegenerative diseases (e.g., Alzheimer's, Parkinson's).
• Mechanistic Biology Research: Used as a tool compound to study the heat shock protein response pathway and cellular stress mechanisms.
• Diabetic Complications Research: Exploration of potential benefits in models of diabetic neuropathy and other complications.
• Cardioprotection Research: Studying its effects in models of ischemic injury and heart failure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Bimoclomol
CAS No.	130493-03-7
Molecular Formula	C₂₁H₃₂N₄O₄
Molecular Weight	404.51 g/mol
Synonyms	N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidoyl chloride; Bimoclomol; BRX-220; Bimoclomol hydrochloride; Bimoclomol mesylate; Arimoclomol analog; HSP co-inducer
EINECS	Contact for details

Quality Control

Our Bimoclomol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.