Description

Dapoxetine Hydrochloride CAS NO 129938-20-1 is a selective serotonin reuptake inhibitor (SSRI) specifically developed for the treatment of premature ejaculation (PE) in men. Its primary value lies in its rapid onset of action and short half-life, making it uniquely suited for on-demand use. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing and producing prescription medications for urological and sexual health disorders.

Application

• Primary use as the active pharmaceutical ingredient (API) in prescription medications for the treatment of premature ejaculation (PE).
• Formulation into various solid oral dosage forms, including tablets and capsules, for on-demand therapeutic use.
• Utilization in clinical research and development for new urological and sexual health treatments.
• Manufacturing of generic pharmaceutical products following patent expirations in various markets.
• Supply to contract development and manufacturing organizations (CDMOs) for client-specific drug production.
• Potential use in veterinary pharmaceutical research for related behavioral applications.

Basic Information

Product Name	Dapoxetine Hydrochloride
CAS No.	129938-20-1
Molecular Formula	C21H23NO•HCl
Molecular Weight	341.87 g/mol (Hydrochloride salt)
Synonyms	(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride; Dapoxetine HCl; LY 210448; Priligy (Brand Name); 1-[3-(Dimethylamino)propyl]-1-phenyl-3-naphthalen-1-oxypropylamine hydrochloride; (S)-Dapoxetine hydrochloride; (+)-Dapoxetine hydrochloride
EINECS	Contact for details

Quality Control

Our Dapoxetine Hydrochloride is manufactured under strict quality systems. We ensure compliance with ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and relevant pharmacopeial standards. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, available upon request. Our commitment to cGMP (current Good Manufacturing Practice) principles guarantees product consistency and traceability for our global pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Optical Rotation	Specific range provided on COA
Particle Size Distribution	Available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.