Description

2,5-Morpholinedione,3,6-Dimethyl-,(3R-Trans)-(9Ci) is a high-purity chiral morpholinedione derivative, a key building block in advanced organic synthesis. Its stereochemically defined structure makes it a critical intermediate for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for constructing complex heterocyclic frameworks.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands or organocatalysts for synthetic applications.

Basic Information

Product Name	2,5-Morpholinedione,3,6-Dimethyl-,(3R-Trans)-(9Ci)
CAS No.	129880-51-9
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	(3R,6R)-3,6-Dimethyl-1,4-morpholine-2,5-dione; (3R,6R)-3,6-Dimethylmorpholine-2,5-dione; (R,R)-3,6-Dimethyl-1,4-dioxane-2,5-dione; (R,R)-3,6-Dimethyl-2,5-morpholinedione; (3R-trans)-3,6-Dimethyl-2,5-morpholinedione; D-Lactide (Note: Confirm stereochemistry); Cyclic D,L-lactic acid dimer (stereospecific).
EINECS	Contact for details

Quality Control

Our 2,5-Morpholinedione,3,6-Dimethyl-,(3R-Trans)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, and stereochemical integrity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.