Description

Methyl 4-Boc-Piperazine-2-Carboxylate CAS NO 129799-08-2 is a high-purity, protected piperazine derivative serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in the orthogonal protection of the piperazine nitrogen and carboxylic acid groups, enabling precise, sequential reactions essential for constructing complex molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing a functionalized piperazine core.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities for various therapeutic targets.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for creating novel peptide-like structures with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the construction of molecular tools and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and the cGMP production of advanced intermediates.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Methyl 4-Boc-Piperazine-2-Carboxylate
CAS No.	129799-08-2
Molecular Formula	C12H22N2O4
Molecular Weight	258.31 g/mol
Synonyms	Methyl 4-(tert-Butoxycarbonyl)piperazine-2-carboxylate; 1-Boc-3-Carbomethoxypiperazine; 4-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid methyl ester; 1-tert-Butyl 2-methyl 1,4-piperazinedicarboxylate; Methyl 1-Boc-piperazine-2-carboxylate; 2-Piperazinecarboxylic acid, 4-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Methyl 4-(Boc)piperazine-2-carboxylate; 1-N-Boc-3-methoxycarbonylpiperazine
EINECS	Contact for details

Quality Control

Our Methyl 4-Boc-Piperazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.