Description

2-Piperazinecarboxylic Acid, Ethyl Ester, Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily used by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing piperazine or morpholine scaffolds.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, including potential treatments for central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced crop protection agents and pesticides.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide analogs and enzyme inhibitors.
• Chemical Biology Probes: Utilized as a scaffold for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized fine chemicals.

Basic Information

Product Name	2-Piperazinecarboxylic Acid, Ethyl Ester, Dihydrochloride
CAS No.	129798-91-0
Molecular Formula	C7H16N2O2 • 2HCl
Molecular Weight	241.13 g/mol (free base: 172.22 g/mol)
Synonyms	Ethyl 2-Piperazinecarboxylate Dihydrochloride; Ethyl Piperazine-2-carboxylate Dihydrochloride; 2-Carbethoxypiperazine Dihydrochloride; 1,4-Piperazinedicarboxylic Acid, 2-Ethyl Ester, Dihydrochloride; Ethyl Piperazine-2-carboxylate Hydrochloride; NSC 339539 Dihydrochloride; Piperazine-2-carboxylic Acid Ethyl Ester Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylic Acid, Ethyl Ester, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.