Description

(1S)-1β,8Aβ-Dihydroxy-1,4-Dimethyl-7-Isopropylidene-1,2,3,3A,8,8A-Hexahydroazulen-6(7H)-One is a high-purity sesquiterpene derivative with a complex, functionalized azulene core structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, valued for its unique stereochemistry and reactivity. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents and bioactive molecules.
• Asymmetric Synthesis: Utilized as a sophisticated building block for constructing complex natural products and fragrances.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Serves as an analytical standard for quality control and method development in R&D and manufacturing.
• Academic & Industrial R&D: Used in exploratory chemistry for developing new synthetic methodologies and catalysts.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals with high added value.

Basic Information

Product Name	(1S)-1β,8Aβ-Dihydroxy-1,4-Dimethyl-7-Isopropylidene-1,2,3,3A,8,8A-Hexahydroazulen-6(7H)-One
CAS No.	129673-90-1
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	(1S,3aS,8aβ)-1,8a-Dihydroxy-1,4-dimethyl-7-(propan-2-ylidene)-1,2,3,3a,8,8a-hexahydroazulen-6-one; 1,8a-Dihydroxy-1,4-dimethyl-7-isopropylidene-1,2,3,3a,8,8a-hexahydroazulen-6-one; (1S,3aS,8aR)-1,8a-Dihydroxy-1,4-dimethyl-7-(prop-1-en-2-yl)-2,3,3a,8,8a,9-hexahydro-1H-cyclopenta[a]naphthalen-6(7H)-one; Sesquiterpene derivative; Azulene derivative; Chiral sesquiterpenoid
EINECS	Contact for details

Quality Control

Our (1S)-1β,8Aβ-Dihydroxy-1,4-Dimethyl-7-Isopropylidene-1,2,3,3A,8,8A-Hexahydroazulen-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.