Description

Picras-3-Ene-2,16-Dione, 11,20-Epoxy-1,11,12,14,15-Pentahydroxy-, (1β,11β,12α,15β)- CAS NO 129587-06-0 is a highly functionalized diterpenoid quinone methide, a class of compounds known for their complex molecular architecture and significant biological activity. This compound is of substantial interest for its role as a key intermediate or reference standard in advanced pharmaceutical research and natural product chemistry. It is primarily sought by research institutions and pharmaceutical developers focused on oncology, anti-inflammatory agents, and novel bioactive compound discovery. The intricate polyhydroxy and epoxy functionalities make it a valuable scaffold for studying structure-activity relationships and developing new therapeutic leads.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block for synthesizing novel drug candidates, particularly in anti-cancer and anti-inflammatory therapeutic areas.
• Natural Product Chemistry: Used as an authentic standard for the isolation, identification, and quantification of related diterpenoids from plant extracts like Picrasma species.
• Biochemical Research: Employed in mechanistic studies to investigate biological pathways, enzyme inhibition, and cellular signaling processes due to its bioactive quinone methide core.
• Academic Research: Utilized in universities and research institutes for synthetic chemistry projects, total synthesis endeavors, and pharmacological screening assays.
• High-Purity Chemical Supply: Supplied to fine chemical distributors and catalog companies for inclusion in specialized chemical libraries for high-throughput screening.

Basic Information

Product Name	Picras-3-Ene-2,16-Dione, 11,20-Epoxy-1,11,12,14,15-Pentahydroxy-, (1β,11β,12α,15β)-
CAS No.	129587-06-0
Molecular Formula	C₂₀H₂₄O₉
Molecular Weight	408.40 g/mol
Synonyms	11,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-en-2,16-dione; (1β,11β,12α,15β)-11,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-en-2,16-dione; Nigakilactone F; Picrasin S; Quassinoid Diterpene; Isoterchebin (related compound); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the identity, purity, and consistency of our high-value research chemicals. Each batch of Picras-3-Ene-2,16-Dione, 11,20-Epoxy-1,11,12,14,15-Pentahydroxy-, (1β,11β,12α,15β)- is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification data is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.