Description

2,2,2-Trifluoro-n-Pyrazin-2-Ylacetamide is a high-purity fluorinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique trifluoroacetamide moiety, which imparts desirable metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorine atoms to enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a starting material for creating fluorinated heterocyclic compounds used in organic electronics and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in probe design.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,2,2-Trifluoro-n-Pyrazin-2-Ylacetamide
CAS No.	129476-64-8
Molecular Formula	C6H4F3N3O
Molecular Weight	191.11 g/mol
Synonyms	2,2,2-Trifluoro-N-(pyrazin-2-yl)acetamide; 2,2,2-Trifluoroacetamide, N-2-pyrazinyl-; N-Pyrazin-2-yl-2,2,2-trifluoroacetamide; 2-Pyrazinyl-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-2-pyrazinylacetamide; Trifluoroacetamide pyrazine derivative; 2-(Trifluoroacetamido)pyrazine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-Pyrazin-2-Ylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.