Description

2-(4-Allyl-1-Piperazinyl)-4-Phenoxyquinazoline Fumarate is a high-purity, specialized organic compound with a complex heterocyclic structure, serving as a critical intermediate in advanced pharmaceutical research and development. Its value lies in its role as a key building block for synthesizing novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. This product is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new molecular entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel quinazoline-based drug candidates targeting specific biological pathways.
• Research Chemical: Used in academic and industrial research settings for studying structure-activity relationships (SAR) and developing new pharmacophores.
• API Synthesis: Serves as a building block in the production of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trial materials.
• Neurological & Psychiatric Drug Development: Its structural features make it relevant for research into compounds targeting neurological receptors and enzymes.
• Oncology Research: Potential use in the synthesis of kinase inhibitors and other targeted cancer therapies under investigation.
• Chemical Biology Probes: Can be utilized to create molecular probes for understanding protein function and cellular signaling mechanisms.

Basic Information

Product Name	2-(4-Allyl-1-Piperazinyl)-4-Phenoxyquinazoline Fumarate
CAS No.	129112-70-5
Molecular Formula	C25H26N4O5
Molecular Weight	462.50 g/mol
Synonyms	2-(4-Allylpiperazin-1-yl)-4-phenoxyquinazoline fumarate; 4-Phenoxy-2-(4-allyl-1-piperazinyl)quinazoline fumarate; 129112-70-5; Fumaric acid, compd. with 2-(4-allyl-1-piperazinyl)-4-phenoxyquinazoline (1:1); Quinazoline, 2-(4-allyl-1-piperazinyl)-4-phenoxy-, fumarate (1:1)
EINECS	Contact for details

Quality Control

Our 2-(4-Allyl-1-Piperazinyl)-4-Phenoxyquinazoline Fumarate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable for non-clinical grade materials, ensuring traceability and documentation for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.