Description

(±)16-Hete CAS NO 128914-46-5 is a synthetic hydroxy-eicosatetraenoic acid (HETE) derivative, a key intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways. This compound is of significant value for researchers and manufacturers developing novel therapeutic agents and biochemical probes targeting inflammation and related disorders. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for drug discovery, metabolic studies, and as a reference standard.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel anti-inflammatory and immunomodulatory drug candidates.
• Biochemical Research: Used as a reference standard and probe in studies of eicosanoid biology, lipoxygenase enzyme activity, and arachidonic acid metabolism.
• Metabolite Standard: Serves as an analytical standard in LC-MS, HPLC, and GC-MS for the quantification of HETE metabolites in biological samples.
• Cell Signaling Studies: Employed in vitro and in vivo research to investigate the role of specific HETEs in cellular signaling pathways.
• Academic & Contract Research: Essential material for universities and CROs conducting fundamental research in biochemistry and pharmacology.

Basic Information

Product Name	(±)16-Hete
CAS No.	128914-46-5
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	16-HETE; 16-Hydroxyeicosatetraenoic Acid; (±)-16-HETE; 16(S)-HETE Racemate; 16-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 16-HETE-d8 (unlabeled analog); Arachidonic Acid, 16-hydroxy-; 16-Hydroxyarachidonic Acid
EINECS	Contact for details

Quality Control

Our (±)16-Hete is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.