Description

Aniline Hydrochloride, [14C(U)] is a carbon-14 radiolabeled derivative of aniline hydrochloride, a fundamental aromatic amine salt. This isotopically labeled compound is essential for advanced metabolic, pharmacokinetic, and environmental fate studies, providing critical traceability in complex biological and chemical systems. It is primarily utilized by researchers and scientists in pharmaceutical development, agrochemical research, and environmental toxicology who require precise tracking of molecular pathways.

Application

• Tracer Studies in Pharmaceutical R&D: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of new chemical entities and their metabolites.
• Agrochemical Metabolism Research: Employed in studies to understand the metabolic breakdown and environmental degradation pathways of aniline-based pesticides and herbicides.
• Biochemical Pathway Analysis: Serves as a tool in fundamental biochemical research to elucidate specific enzymatic reactions and metabolic routes involving aromatic amines.
• Environmental Fate and Ecotoxicology Studies: Applied to track the persistence, transformation, and bioaccumulation of aniline-related compounds in environmental models.
• Synthesis of Labeled Complex Molecules: Acts as a key radiolabeled building block for the synthesis of more complex carbon-14 labeled compounds for research purposes.
• Quality Control and Method Development: Used as an internal standard or reference material in the development and validation of analytical methods such as LC-MS/MS or radio-HPLC.

Basic Information

Product Name	Aniline Hydrochloride, [14C(U)]
CAS No.	128884-30-0
Molecular Formula	C6H7N • HCl (with uniform 14C labeling in the phenyl ring)
Molecular Weight	~129.59 g/mol (exact mass depends on specific activity)
Synonyms	Aniline Hydrochloride-14C(U); Benzenamine Hydrochloride-14C(U); Phenylamine Hydrochloride-14C(U); Aniline HCl-14C; [U-14C]Aniline Hydrochloride; Carbon-14 Labeled Aniline Hydrochloride; Radiolabeled Aniline HCl; Anilinium Chloride-14C
EINECS	Contact for details

Quality Control

Every batch of our Aniline Hydrochloride, [14C(U)] is produced and analyzed under strict quality systems to ensure high chemical and radiochemical purity, precise specific activity, and isotopic uniformity. Comprehensive release testing includes identity confirmation, assay, radiochemical purity determination, and solvent residue analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical parameters and traceability to relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider conditions recommended for radiolabeled compounds to minimize radiolytic decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC / Titration)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customer specified (mCi/mmol)
Solvent Residues (GC)	Meets ICH guidelines
Uniformity of Labeling	Confirmation provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.