Description

4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6,6-Dibromo-3,3-Dimethyl-7-Oxo-, 4-Oxide, (2S,5R)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is critical for the synthesis of novel β-lactam antibiotics and serves as a key building block in medicinal chemistry research. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antimicrobial agents and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel β-lactam antibiotic candidates.
• Antimicrobial Research: Used as a core scaffold in medicinal chemistry for the design and development of new antibacterial agents.
• Process Chemistry: Serves as a starting material or intermediate in process development and scale-up for active pharmaceutical ingredient (API) manufacturing.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems with potential biological activity.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for studying structure-activity relationships (SAR) and reaction mechanisms.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6,6-Dibromo-3,3-Dimethyl-7-Oxo-, 4-Oxide, (2S,5R)-
CAS No.	128657-18-1
Molecular Formula	C9H9Br2NO4S
Molecular Weight	387.04 g/mol
Synonyms	(2S,5R)-6,6-Dibromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide; 6,6-Dibromopenicillanic acid S,S-dioxide; Dibromopenicillanic acid sulfone; (2S,5R)-6,6-Dibromopenicillanic acid sulfone; 6α,6β-Dibromopenicillanic acid S,S-dioxide; Penicillanic acid, 6,6-dibromo-, 4,4-dioxide, (2S,5R)-; DBPA sulfone
EINECS	Contact for details

Quality Control

Our 4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6,6-Dibromo-3,3-Dimethyl-7-Oxo-, 4-Oxide, (2S,5R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets exacting pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) with full traceability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2S,5R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.