Description

3-Azetidinecarbonyl Chloride, 1-Nitro- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride group and a nitro substituent on the azetidine ring. This compound is of significant value in advanced organic synthesis, enabling the efficient introduction of the 1-nitroazetidine-3-carbonyl moiety into target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or activity-based probes to study biological pathways and enzyme functions.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Essential reagent for methodology development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Item	Details
Product Name	3-Azetidinecarbonyl Chloride, 1-Nitro- (9Ci)
CAS No.	128534-31-6
Molecular Formula	C4H5ClN2O3
Molecular Weight	164.55 g/mol
Synonyms	1-Nitroazetidine-3-carbonyl chloride; 1-Nitro-3-azetidinecarbonyl chloride; 3-(Chlorocarbonyl)-1-nitroazetidine; 1-Nitroazetidine-3-carboxylic acid chloride; Azetidine-3-carbonyl chloride, 1-nitro-; (1-Nitroazetidin-3-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Azetidinecarbonyl Chloride, 1-Nitro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC/NMR), impurity profile, and physical characteristics are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.