Description

(S)-2-Ethyl-Piperazine-2Hcl is a high-purity chiral piperazine derivative, specifically the (S)-enantiomer of 2-ethylpiperazine dihydrochloride. This compound is a critical chiral building block and intermediate valued for its role in the synthesis of enantiomerically pure pharmaceuticals and advanced organic molecules. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is paramount for biological activity and product efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, antivirals, and receptor antagonists.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for asymmetric catalysis, enabling the production of enantiomerically enriched compounds.
• Agrochemical Research: Serves as a building block for creating novel chiral pesticides and herbicides with improved selectivity and environmental profile.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, specialty chemicals, and other high-value chiral compounds.
• Academic & R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies in university and industrial laboratories.

Basic Information

Product Name	(S)-2-Ethyl-Piperazine-2Hcl
CAS No.	128427-05-4
Molecular Formula	C6H16Cl2N2
Molecular Weight	187.11 g/mol
Synonyms	(S)-2-Ethylpiperazine Dihydrochloride; (S)-2-Ethylpiperazine-2HCl; (S)-2-Ethylpiperazine Hydrochloride; (2S)-2-Ethylpiperazine Dihydrochloride; (S)-(-)-2-Ethylpiperazine Dihydrochloride; (S)-2-Ethylpiperazine Dihydrochloride Salt; (S)-2-Ethylpiperazine-2,2HCl; (S)-2-Ethylpiperazine.2HCl
EINECS	Contact for details

Quality Control

Our (S)-2-Ethyl-Piperazine-2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the stringent requirements for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.