Description

2-(Chloromethyl)-5-Methylpyrazine Hydrochloride is a high-purity, functionalized pyrazine derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic building block for synthesizing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Building block for creating new-generation pesticides, herbicides, and fungicides with pyrazine-based active moieties.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic applications.
• Material Science Research: Intermediate for synthesizing organic electronic materials and functional polymers.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and biochemical tools.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(Chloromethyl)-5-Methylpyrazine Hydrochloride
CAS No.	128229-06-1
Molecular Formula	C6H8ClN2•HCl
Molecular Weight	193.06 g/mol
Synonyms	5-Methyl-2-(chloromethyl)pyrazine hydrochloride; 2-Chloromethyl-5-methylpyrazine hydrochloride; (5-Methylpyrazin-2-yl)methyl chloride hydrochloride; 5-Methyl-2-pyrazinemethyl chloride hydrochloride; 2-(Chloromethyl)-5-methylpyrazine HCl; 2-(Chloromethyl)-5-methylpyrazine monohydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-5-Methylpyrazine Hydrochloride is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.