Description

1-(Piperidin-4-Yl)Imidazolidin-2-One Hydrochloride is a high-purity organic salt compound, primarily utilized as a sophisticated pharmaceutical intermediate. Its core value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This product is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the research and production of new APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies.

Basic Information

Product Name	1-(Piperidin-4-Yl)Imidazolidin-2-One Hydrochloride
CAS No.	128225-38-7
Molecular Formula	C8H16ClN3O
Molecular Weight	205.69 g/mol
Synonyms	1-(4-Piperidinyl)-2-imidazolidinone hydrochloride; 1-(Piperidin-4-yl)imidazolidin-2-one HCl; 2-Imidazolidinone, 1-(4-piperidinyl)-, hydrochloride; 1-(4-Piperidyl)imidazolidin-2-one hydrochloride; 1-(Piperidin-4-yl)-2-imidazolidinone monohydrochloride; 128225-38-7 (CAS); 1-Piperidin-4-yl-imidazolidin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-Yl)Imidazolidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.