Description

Tr-Peg7-Alcohol CAS NO 127999-16-0 is a high-purity, branched polyethylene glycol (PEG) derivative featuring a tri-functional core and seven ethylene oxide units terminated with a hydroxyl group. This unique molecular architecture provides enhanced solubility, tunable hydrophilicity, and multiple reactive sites, making it a critical intermediate for advanced material synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors who require precise PEGylation agents and functional polymer building blocks.

Application

• Pharmaceutical PEGylation: A key linker or spacer for conjugating therapeutic proteins, peptides, and small molecule drugs to improve pharmacokinetics, solubility, and stability.
• Bioconjugation Chemistry: Serves as a versatile heterobifunctional crosslinker for attaching labels, probes, or other molecules to biomolecules in diagnostic assay development.
• Polymer & Material Science: Acts as a functional initiator or monomer for synthesizing star-shaped, branched, or hyperbranched polymers with tailored properties for hydrogels, coatings, and drug delivery systems.
• Surface Modification: Used to create hydrophilic, protein-resistant, and biocompatible coatings on nanoparticles, medical devices, and sensor surfaces.
• Solubility & Formulation Enhancer: Improves the aqueous solubility and bioavailability of poorly soluble active compounds in cosmetic and pharmaceutical formulations.
• Chemical Synthesis Intermediate: Provides a polyether backbone for further functionalization (e.g., with amines, carboxylates, or maleimides) to create custom specialty chemicals.

Basic Information

Product Name	Tr-Peg7-Alcohol
CAS No.	127999-16-0
Molecular Formula	C27H56O16
Molecular Weight	636.73 g/mol
Synonyms	Tri-PEG7-alcohol; Tris-PEG7-OH; 2,2',2''-(Ethane-1,1,1-triyl)tris(ethane-2,1-diyl) tris(oxy)triaconta-3,6,9,12,15,18,21-heptaol; 1,1,1-Tris(hydroxymethyl)ethane PEG7 derivative; PEGylated Trimethylolpropane (TMP) derivative; Branched PEG heptamer alcohol; Heterofunctional PEG Trimer
EINECS	Contact for details

Quality Control

Our Tr-Peg7-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and cGMP-grade applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, purity, and critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.