Description

Benzoyl Fluoride, 4-(Methylthio)- (9Ci) is a specialized organofluorine building block characterized by the presence of both a benzoyl fluoride and a methylthio functional group. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex sulfur- and fluorine-containing molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thioether or fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the methylthio group can modulate biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and specialty materials with tailored properties.
• Ligand and Catalyst Development: Employed in the preparation of sulfur-containing ligands for metal catalysis and organocatalysts.
• Fluorination Reagent: Utilized as a source of the benzoyl fluoride moiety in transfer fluorination reactions under controlled conditions.
• Chemical Biology Probes: Used to synthesize molecular probes for studying enzyme mechanisms and protein interactions involving sulfur metabolism.

Basic Information

Product Name	Benzoyl Fluoride, 4-(Methylthio)- (9Ci)
CAS No.	127743-98-0
Molecular Formula	C8H7FOS
Molecular Weight	170.20 g/mol
Synonyms	4-(Methylthio)benzoyl Fluoride; p-(Methylthio)benzoyl Fluoride; 4-Methylsulfanylbenzoyl Fluoride; 4-(Methylmercapto)benzoyl Fluoride; Benzoyl fluoride, 4-(methylthio)-; 4-Methylthiobenzoyl fluoride
EINECS	Contact for details

Quality Control

Every batch of Benzoyl Fluoride, 4-(Methylthio)- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), identity confirmation (by IR, NMR), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.