Description

5(S)-Hete Lactone is a high-purity chiral lactone compound, identified by CAS NO 127708-42-3, serving as a critical advanced intermediate in organic synthesis. Its value lies in its stereochemical purity, which is essential for producing enantiomerically defined active pharmaceutical ingredients (APIs) and fine chemicals. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of prostaglandin analogs and other bioactive molecules.
• Organic Synthesis: Used in asymmetric synthesis and cyclization reactions to construct complex heterocyclic structures.
• Agrochemical Research: Intermediate in the development of novel, stereospecific pesticides and plant growth regulators.
• Flavor & Fragrance Industry: Potential precursor for the synthesis of specific lactone-based aroma compounds.
• Academic & R&D: Valuable reference standard and starting material for methodological studies in synthetic chemistry.

Basic Information

Product Name	5(S)-Hete Lactone
CAS No.	127708-42-3
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	5(S)-HETE Lactone; (5S)-Hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic Acid Lactone; 5(S)-HETE-δ-lactone; 5S-HETE Lactone; 5(S)-HETEL; 5S-Hydroxyeicosatetraenoic Acid Lactone; 5(S)-HETE-1,5-lactone
EINECS	Contact for details

Quality Control

Our 5(S)-Hete Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by NMR and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.