Description

1β-Hydroxy Vitamin D2 is a key synthetic derivative of ergocalciferol (Vitamin D2) designed for advanced pharmaceutical and research applications. This compound is valued for its role as a metabolic precursor and research tool in studying vitamin D pathways and developing therapeutic agents. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and life science research sectors for developing treatments related to bone health, calcium regulation, and endocrine disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced vitamin D analogs and active pharmaceutical ingredients (APIs) for therapeutic use.
• Nutraceutical Research: Used in the development and study of high-potency dietary supplements targeting vitamin D deficiency.
• Biochemical Research: Serves as a reference standard and tool compound for investigating vitamin D metabolism, receptor binding, and signaling pathways in academic and industrial R&D.
• Endocrinology Studies: Applied in preclinical research for conditions related to parathyroid function, calcium homeostasis, and bone mineralization.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	1β-Hydroxy Vitamin D2
CAS No.	127516-23-8
Molecular Formula	C28H44O2
Molecular Weight	412.65 g/mol
Synonyms	1β-Hydroxyergocalciferol; 1β-OH Vitamin D2; 1β-Hydroxyvitamin D2; (5Z,7E,22E)-(1S,3R)-1,3-Dihydroxy-9,10-secoergosta-5,7,10(19),22-tetraene; 1β,25-Dihydroxyvitamin D2 (Note: This is a related metabolite); 1β-Hydroxycalciferol; 1β-OH-D2
EINECS	Contact for details

Quality Control

Our 1β-Hydroxy Vitamin D2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.