Description

(R)-3-Aminopiperidine CAS NO 127294-73-9 is a high-purity chiral piperidine derivative, serving as a critical building block in asymmetric synthesis. Its value lies in providing a stereochemically defined amine handle for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potent drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Research: Employed in the design and synthesis of new-generation, stereospecific herbicides and pesticides.
• Peptidomimetics & Molecular Scaffolds: Integral for constructing constrained peptide analogs and privileged scaffolds in medicinal chemistry.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services at various scales.

Basic Information

Product Name	(R)-3-Aminopiperidine
CAS No.	127294-73-9
Molecular Formula	C5H12N2
Molecular Weight	100.16 g/mol
Synonyms	(R)-(+)-3-Aminopiperidine; (3R)-Piperidin-3-amine; (R)-3-Piperidinamine; (R)-Piperidin-3-ylamine; (+)-3-Aminopiperidine; (R)-3-APD; (R)-3-AP; UNII-7Q2K5F8T0F
EINECS	Contact for details

Quality Control

We supply (R)-3-Aminopiperidine in high chemical and enantiomeric purity grades suitable for advanced research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed specifications for identity, purity (by HPLC), chiral purity (by chiral HPLC), and residual solvents are available upon request. We adhere to cGMP principles for production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen/argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.