Description

2-Azabicyclo[3.1.0]Hexane-1-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique fused bicyclic structure. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel chemical entities in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of protease inhibitors due to its constrained bicyclic framework.
• CNS Drug Synthesis: An important precursor in the development of therapeutics targeting the central nervous system.
• Antiviral Agent Research: Employed in the synthetic pathways for investigational antiviral compounds.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthesis.
• Chemical Biology Probes: Used to create molecular tools for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Azabicyclo[3.1.0]Hexane-1-Carboxylic Acid Hydrochloride
CAS No.	127117-42-4
Molecular Formula	C7H11NO2 • HCl
Molecular Weight	177.63 g/mol
Synonyms	1-Azabicyclo[3.1.0]hexane-2-carboxylic acid hydrochloride; (1R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid hydrochloride; 2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, hydrochloride; 3-Carboxy-2-azabicyclo[3.1.0]hexane hydrochloride; 2-Aza-3-bicyclo[3.1.0]hexanecarboxylic acid hydrochloride; (1S,5R)-3-Carboxy-2-azabicyclo[3.1.0]hexane hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[3.1.0]Hexane-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.