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13-Acetoxy-3Beta-Hydroxygermacra-1(10)E,4E,7(11)-Trien-12,6Alpha-Olide CAS NO 126829-66-1


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CAS No.:126829-66-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

13-Acetoxy-3Beta-Hydroxygermacra-1(10)E,4E,7(11)-Trien-12,6Alpha-Olide CAS NO 126829-66-1 is a high-purity sesquiterpene lactone derivative, a compound of significant interest in advanced chemical synthesis and research. Its complex molecular architecture makes it a valuable intermediate or reference standard for developing novel bioactive molecules. This product is essential for B2B clients in the pharmaceutical research, fine chemical synthesis, and natural product chemistry sectors who require reliable, high-quality building blocks.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
  • Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of related sesquiterpenoids.
  • Natural Product Synthesis: Acts as a sophisticated starting material or intermediate for the total or semi-synthesis of complex natural products and their analogs.
  • Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) and the biological mechanisms of germacranolide-type compounds.
  • Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name 13-Acetoxy-3Beta-Hydroxygermacra-1(10)E,4E,7(11)-Trien-12,6Alpha-Olide
CAS No. 126829-66-1
Molecular Formula C17H22O5
Molecular Weight 306.36 g/mol
Synonyms 13-Acetoxy-3β-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6α-olide; 3β-Acetoxy-13-hydroxygermacra-1(10),4,7(11)-trien-12,6α-olide (isomer); Germacranolide derivative; Sesquiterpene lactone acetate; (3β,6α)-13-(Acetyloxy)-3-hydroxygermacra-1(10),4,7(11)-trien-12,6-olide
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Quality Control

Our 13-Acetoxy-3Beta-Hydroxygermacra-1(10)E,4E,7(11)-Trien-12,6Alpha-Olide is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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